The work is devoted to the influence of a new vitamin-mineral feed additive on the bees. During its development, we used some new approaches aimed at increasing the bioavailability of vitamins and microelements, and also at solving the problem associated with the occurrence of undesirable chemical reactions between substances. At the same time, the potential possibility of physiological (biochemical) antagonism or synergism of the substances used was taken into account. e feed additive consists of two parts having different composition and assigned to bees separately. e aim of the work was to compare the safety for bees of the proposed feed additive and feed additive with the same content of nutrients, vitamins, macro- and microelements, but without separation of the components. e study was carried out using of cage- tests using generally accepted methods. e dynamics of death and the average life expectancy of bees in the bee cages were studied. The studied feed additives were fed to the bees together with sugar syrup for 8 days. An increase in the average life expectancy of bees that received a new feed additive compared to bees that received a feed additive without separation of components by 1.4 and 1.5 times, respectively, was revealed