<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vetpatol</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринарная патология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Veterinary Pathology</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-4826</issn><publisher><publisher-name>Don State Technical University</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vetpatol-233</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Внутренние незаразные болезни</subject></subj-group></article-categories><title-group><article-title>РАСШИРЕНИЕ АРЕАЛА BABESIA GIBSONI. НОВЫЙ ЭТИОЛОГИЧЕСКИЙ ФАКТОР БАБЕЗИОЗА В РОСТОВСКОЙ ОБЛАСТИ</article-title><trans-title-group xml:lang="en"><trans-title>EXPANSION OF THE BABESIA GIBSONI AREA. NEW ETIOLOGICAL FACTOR OF BABEZIOSIS IN THE ROSTOV REGION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карташов</surname><given-names>Сергей Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Kartashov</surname><given-names>Sergey</given-names></name></name-alternatives><email xlink:type="simple">kartashovsn@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермаков</surname><given-names>Алексей Михайлович</given-names></name><name name-style="western" xml:lang="en"><surname>Yermakov</surname><given-names>Alexey Mikhailovich</given-names></name></name-alternatives><email xlink:type="simple">amermakov@ya.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ключников</surname><given-names>Александр</given-names></name><name name-style="western" xml:lang="en"><surname>Klyuchnikov</surname><given-names>Alexander</given-names></name></name-alternatives><email xlink:type="simple">alex-roz@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бутенков</surname><given-names>Александр Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Butenkov</surname><given-names>Alexander</given-names></name></name-alternatives><email xlink:type="simple">butencov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карташова</surname><given-names>Евгения Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Kartashova</surname><given-names>Evgenia Vladimirovna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аксенова</surname><given-names>Полина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Aksenova</surname><given-names>Polina</given-names></name></name-alternatives><email xlink:type="simple">polinax-1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ДГТУ</institution><country>Russian Federation</country></aff><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ДГТУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>amermakov@ya.ru</institution><country>Russian Federation</country></aff></aff-alternatives><aff xml:lang="ru" id="aff-3"><institution>ветеринарная клиника «Вита»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>20</day><month>03</month><year>2017</year></pub-date><volume>0</volume><issue>1</issue><fpage>24</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Карташов С.Н., Ермаков А.М., Ключников .А., Бутенков А.И., Карташова Е.В., Аксенова  П.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Карташов С.Н., Ермаков А.М., Ключников .А., Бутенков А.И., Карташова Е.В., Аксенова  П.В.</copyright-holder><copyright-holder xml:lang="en">Карташов С.Н., Yermakov A.M., Ключников .А., Бутенков А.И., Kartashova E.V., Аксенова  П.В.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vetpat.ru/jour/article/view/233">https://www.vetpat.ru/jour/article/view/233</self-uri><abstract><p>Данная статья посвящена случаю бабезиоза у собаки с новым для России этиологическим агентом B. gibsoni. На сегодняшний день по этиологическим агентам выделяют три формы бабезиоза (пироплазмоза) собак. Первая этиологическая форма бабезиоза является космополитической и широко распространенной в Европе и России. Она вызывается B. canis и B. vogeli. Вторая форма встречается в основном в Африке, ее возбудителем являются B. rossi. Третья форма считается эндемичной для Азии, Африки и Северной Америки, ее возбудитель - B. gibsoni, ее наличие в Европе и России вызывает сомнение. Нами установлено наличие Babesia gibsoni в паразитофауне Ростовской области. При этом заболевание бабезиозом протекало атипично. Отмечались неустойчивый аппетит, периодическая слабость и бледность слизистых оболочек, гиперхромная анемия, нейтрофильный лейкоцитоз, тромбоцитопения, незначительное повышения печеночных трансфераз и щелочной фосфатазы.  Определено, что в сложных случаях рецидивирующих и упорно протекающих анемий неизвестной этиологии необходимо исключить возбудителя бабезиоза  методом ПЦР.  scientific</p></abstract><trans-abstract xml:lang="en"><p>This article is devoted to the case of babesiosis in a dog with a new for Russia etiological agent B. gibsoni. Now there are three forms of babesiosis (pyroplasmosis) in dogs. The first etiologic form of babesiosis is widespread in Europe and Russia. It is caused by B. canis and B. vogeli. The second form is found mainly in Africa, its causative agent is B. rossi. The third form is considered endemic for Asia, Africa and North America, its causative agent is B. gibsoni. Its presence in Europe and Russia is questionable. We found the presence of Babesia gibsoni into the parasitofauna of the Rostov region. The disease with babesiosis was atypical. There was an unstable appetite, periodic, weak and pallor of the mucous membranes, hyperchromic anemia, neutrophilic leukocytosis, thrombocytopenia, and slight increase in hepatic transferases and alkaline phosphatase. It was determined that in complex cases of recurrent anemia of unknown etiology, it is necessary to exclude the causative agent of babesiosis by the PCR method.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Babesia gibsoni</kwd><kwd>бабезиоз</kwd><kwd>пироплазмоз</kwd><kwd>собаки</kwd><kwd>ПЦР-диагностика</kwd><kwd>этиология заболевания</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zahler M. (2000). Detection of a new pathogenic Babesia microtilike species in dogs / M. Zahler, H. Rinder, E. Schein, R. Gothe // Veterinary Parasitology, 89: 241-248.</mixed-citation><mixed-citation xml:lang="en">Zahler M. (2000). Detection of a new pathogenic Babesia microtilike species in dogs / M. Zahler, H. Rinder, E. Schein, R. Gothe // Veterinary Parasitology, 89: 241-248.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Chang G. N. (1992). A serological survey of canine babesiosis in Taiwan / G. N. Chang, C. H. Tu // Journal of the Chinese Society of Veterinary Science, 18: 125-131.</mixed-citation><mixed-citation xml:lang="en">Chang G. N. (1992). A serological survey of canine babesiosis in Taiwan / G. N. Chang, C. H. Tu // Journal of the Chinese Society of Veterinary Science, 18: 125-131.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Anderson J. F. (1980). Canine babesiosis: Indirect fluorescent antibody test for a North American isolate of Babesia gibsoni / J. F. Anderson, L. A. Magnarelli, A. J. Sulzer // American Journal of Veterinary Research, 41: 2102-2105.</mixed-citation><mixed-citation xml:lang="en">Anderson J. F. (1980). Canine babesiosis: Indirect fluorescent antibody test for a North American isolate of Babesia gibsoni / J. F. Anderson, L. A. Magnarelli, A. J. Sulzer // American Journal of Veterinary Research, 41: 2102-2105.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kocan A. (2001). A genotypically unique Babesia gibsoni-like parasite recovered from a dog in Oklahoma / A. Kocan, A. Kjemtrup, J. Meinkoth, L. C. Whitworth, G. L. Murphy, L. Decker, M. Loenz // Journal of Parasitology, 87: 437-438</mixed-citation><mixed-citation xml:lang="en">Kocan A. (2001). A genotypically unique Babesia gibsoni-like parasite recovered from a dog in Oklahoma / A. Kocan, A. Kjemtrup, J. Meinkoth, L. C. Whitworth, G. L. Murphy, L. Decker, M. Loenz // Journal of Parasitology, 87: 437-438</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Yamane I. (1994). Serosurvey of Babesia canis, Babesia gibsoni and Ehrlichia canis in pound dogs in California / I. Yamane, I. A. Gardner, C. P. Ryan, M. Levy, J. Urrico, P. A. Conrad // USA. Preventive Veterinary Medicine, 18: 293-304. 6</mixed-citation><mixed-citation xml:lang="en">Yamane I. (1994). Serosurvey of Babesia canis, Babesia gibsoni and Ehrlichia canis in pound dogs in California / I. Yamane, I. A. Gardner, C. P. Ryan, M. Levy, J. Urrico, P. A. Conrad // USA. Preventive Veterinary Medicine, 18: 293-304. 6</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Kjemtrup A. M. Babesiaconradae, sp. nov., a small Kjemtrup A. M. Babesiaconradae, sp. nov., a small</mixed-citation><mixed-citation xml:lang="en">Kjemtrup A. M. Babesiaconradae, sp. nov., a small Kjemtrup A. M. Babesiaconradae, sp. nov., a small</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Yamasaki M. Comparison and phylogenetic analysis of the heat shock protein 70 gene of Babesia parasites from dogs / M. Yamasaki, H. Inokuma, C. Sugimoto, S. Shaw, M. Aktas, M. J. Yabsley, O. Yamato, Y. Maede // Vet. Parasitol. 2007, 145:217-227</mixed-citation><mixed-citation xml:lang="en">Yamasaki M. Comparison and phylogenetic analysis of the heat shock protein 70 gene of Babesia parasites from dogs / M. Yamasaki, H. Inokuma, C. Sugimoto, S. Shaw, M. Aktas, M. J. Yabsley, O. Yamato, Y. Maede // Vet. Parasitol. 2007, 145:217-227</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Jefferies R. Blood, bull terriers and babesiosis: further evidence for direct transmission of Babesiagibsoni in dogs / R. Jefferies, U. M. Ryan, J. Jardine, D. K. Broughton, I. D. Robertson, P. J. Irwin // AustVet J 2007, 85:459-463.</mixed-citation><mixed-citation xml:lang="en">Jefferies R. Blood, bull terriers and babesiosis: further evidence for direct transmission of Babesiagibsoni in dogs / R. Jefferies, U. M. Ryan, J. Jardine, D. K. Broughton, I. D. Robertson, P. J. Irwin // AustVet J 2007, 85:459-463.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Wulansari R. Clindamycin in the treatment of Babesiagibsoni infections in dogs / R. Wulansari, A. Wijaya, H. Ano, Y. Horii, T. Nasu, S. Yamane, S. Makimura // J AmAnimHospAssoc 2003, 39:558- 562.</mixed-citation><mixed-citation xml:lang="en">Wulansari R. Clindamycin in the treatment of Babesiagibsoni infections in dogs / R. Wulansari, A. Wijaya, H. Ano, Y. Horii, T. Nasu, S. Yamane, S. Makimura // J AmAnimHospAssoc 2003, 39:558- 562.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Suzuki K. A possible treatment strategy and clinical factors to estimate the treatment response in Babesiagibsoni infection / K. Suzuki, H. Wakabyashi, M. Takahashi, K. Fukushima, A. Yabuki, Y. Endo // J VetMedSci 2007, 69:563-568.</mixed-citation><mixed-citation xml:lang="en">Suzuki K. A possible treatment strategy and clinical factors to estimate the treatment response in Babesiagibsoni infection / K. Suzuki, H. Wakabyashi, M. Takahashi, K. Fukushima, A. Yabuki, Y. Endo // J VetMedSci 2007, 69:563-568.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
