The purpose of this work was to study the possibility of using a preparation based on succinic acid and an organic phosphorus compound for the correction of hepatoxic syndrome in cows with subclinical ketosis of (Department of therapy and clinical diagnostics with roentgenology of the Kazan State Medical Academy). Criteria for the effectiveness of the drug were the blood values that were studied within 10 days. The total protein, albumin, total bilirubin, activity of aspartate and alanine transaminase, alkaline phosphatase and gamma-glutamine transferase were determined in the serum. In a clinical study, cows with subclinical ketosis also established a violation of the cud, dystonia of proventriculus, marked liver increasing and tenderness. Biochemical status was characterized by hyperbilirubinemia, disproteinemia, disfermentemia. Application of the drug three times in doses of 10-15 ml per animal is increasing the percentage of aminotransferase by 10-35 %, gammaglutamyltransferase by 35 %, serum total bilirubin content by 50-60 %.