This study presents our experience in the prevention and treatment of acute postoperative pain in case of fracture of the forearm bones in dogs during the perioperative period by providing effective multimodal analgesia based on regional anesthesia using brachial plexus blockade by double control using neurostimulation and sonography. 28 animals were divided into 4 equal groups, examined before surgery, the first day after the completion of surgery, 14, 45 and 180 days after surgery for pain and hypersensitivity. Intravenous analgesics IPA (infusion at a constant rate of ketamine) were used to provide anesthesia for animals of groups A (1) and B (1). In group A (2) and B (2), the subjects underwent blockade of the brachial plexus under the double control of neurostimulation and sonography as analgesia for surgery. The difference between groups A and B was that groups B received constant rate infusion of lidocaine 50 μg/kg/min postoperatively for 12 hours. Also, all dogs (n = 28) received NSAIDs within 3 days after surgery. Our study showed that a multimodal approach to pain relief is an effective strategy for achieving these goals, and the use of regional anesthesia methods often serves as the basis for this approach, as evidenced by the conclusions about the complete absence reaction on pain and hypersensitivity after 180 days after surgery in group A (1) in 57.1 % animals; for A (2) and B (1), these numbers turned out to be the same and equaled 71.4 %; in group B (2) there were 85.7 %.