ВЛИЯНИЕ ДМСО НА ЖИЗНЕСПОСОБНОСТЬ ЗАРОДЫШЕЙ МУТАНТНЫХ МЫШЕЙ KITW-Y В УСЛОВИЯХ IN VITRO И ПОСЛЕ КРИОКОНСЕРВАЦИИ
Abstract
It was shown shat the development in vitro of mouse WR +/KitW-Y embryos was more effective than
development of mouse B6 +/ KitW-Y embryos. It means that basic genotype is very important exposure of
the same mutant gene.
The embryos carrying the mutant gene KitW-Y are less viable then the embryo with wild gene at the presence
of 1% DMSO in culture medium. The abundant embryo damage of mice B6 +/KitW-Y during cryopreservation
seems to be explained by a negative DMSO influence.
development of mouse B6 +/ KitW-Y embryos. It means that basic genotype is very important exposure of
the same mutant gene.
The embryos carrying the mutant gene KitW-Y are less viable then the embryo with wild gene at the presence
of 1% DMSO in culture medium. The abundant embryo damage of mice B6 +/KitW-Y during cryopreservation
seems to be explained by a negative DMSO influence.
About the Authors
Н. СахароваRussian Federation
Л. Межевикина
Russian Federation
Е. Вихлянцева
Russian Federation
Т. Суханова
Russian Federation
А. Смирнов
Russian Federation
М. Поцелуева
Russian Federation
В. Шубина
Russian Federation
А. Малашенко
Russian Federation
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