Preview

Russian Journal of Veterinary Pathology

Advanced search

ROLE OF REGIONAL ANESTHESIA IN PREVENTING OF ACUTE POSTOPERATIVE PAIN SYNDROME IN DOGS

https://doi.org/10.25690/VETPAT.2021.11.79.007

Abstract

This study presents our experience in the prevention and treatment of acute postoperative pain in case of fracture of the forearm bones in dogs during the perioperative period by providing effective multimodal analgesia based on regional anesthesia using brachial plexus blockade by double control using neurostimulation and sonography. 28 animals were divided into 4 equal groups, examined before surgery, the first day after the completion of surgery, 14, 45 and 180 days after surgery for pain and hypersensitivity. Intravenous analgesics IPA (infusion at a constant rate of ketamine) were used to provide anesthesia for animals of groups A (1) and B (1). In group A (2) and B (2), the subjects underwent blockade of the brachial plexus under the double control of neurostimulation and sonography as analgesia for surgery. The difference between groups A and B was that groups B received constant rate infusion of lidocaine 50 μg/kg/min postoperatively for 12 hours. Also, all dogs (n = 28) received NSAIDs within 3 days after surgery. Our study showed that a multimodal approach to pain relief is an effective strategy for achieving these goals, and the use of regional anesthesia methods often serves as the basis for this approach, as evidenced by the conclusions about the complete absence reaction on pain and hypersensitivity after 180 days after surgery in group A (1) in 57.1 % animals; for A (2) and B (1), these numbers turned out to be the same and equaled 71.4 %; in group B (2) there were 85.7 %.

About the Authors

M. O. Voronova
LLC «Biocontrol»
Russian Federation


Y. A. Vatnikov
«Peoples' Friendship University of Russia» (PFUR)
Russian Federation


References

1. Краснова Т. Б. Лечение боли. Острая и хроническая боль // Журнал VetPharma. - № 3. - 2017. - С. 58-64

2. Eisenach J. C. Treating and preventing chronic pain: a view from the spinal cord-bonica lecture, asra annual meeting // Reg. Anesth. Pain Med. - 2006. - P. 146-151

3. Woolf C. J. Central sensitization: implications for the diagnosis and treatment of pain // Pain. - 2011. - P. 2-15

4. Kehlet H. Persistent postsurgical pain: risk factors and prevention / H. Kehlet, T. S. Jensen, C. J. Woolf // Lancet. - 2006. - P. 1618-1625

5. Дмитриев Д. В. Методы оценки послеоперационной боли у детей разного возраста // Медицина боли. - 2016. - № 1 (1). - С. 21-25

6. Costigan M. Neuropathic pain: a maladaptive response of the nervous system to damage / M. Costigan, J. Scholz, C. J. Woolf // Annu Rev Neurosci. - 2009. - P. 1-32

7. Grubb T. Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs / T. Grubb, H. Lobprise // Veterinary medicine and sciene. - May 2020. - Vol. 6. - Issue 2. - P. 209-217

8. Vainionpaa. Clinical and Pharmacokinetic Comparison of Ropivacaine and Bupivacaine in Axillary Plexus Block / Vainionpaa, Vilho, Haavisto, Ermo [et al.] // Anesthesia & Analgesia. - September 1995. - Vol. 81. - P. 534-538

9. Овечкин А. М. Послеоперационная боль: состояние проблемы и современные тенденции послеоперационного обезболивания // Регионарная анестезия и лечение острой боли. - 2015. - № 9 (2). - С. 29-39

10. Haroutiunian S. The neuropathic component in persistent postsurgical pain: a systematic literature review / S. Haroutiunian, L. Nikolajsen, N. B. Finnerup, T. S. Jensen // Pain. - 2013. - P. 95-102

11. Eisenach J. C. Treating and preventing chronic pain: a view from the spinal cord-bonica lecture, asra annual meeting // Reg. Anesth. Pain Med. - 2006. - P. 146-151

12. Mathieu. Sciatic Nerve Block Fails in Preventing the Development of Late Stress-Induced Hyperalgesia When High-Dose Fentanyl Is Administered Perioperatively in Rats / Mathieu, A. Me´leine, C. Rivat, E. L. Cahana, P. Richebe // Regional anaesthesia and pain medicine. - # 37 (4). - P. 448-454

13. Julius D. Molecular mechanisms of nociception / D. Julius, A. L. Basbaum // Nature. - 2001. - P. 203-210

14. Корнюшенков Е. А. Общие вопросы анестезиологии и интенсивной терапии мелких домашних животных / Е. А. Корнюшенков. - М.: Изд. ООО «Сам Полиграфист», 2017. - 59 с

15. Haroutiunian S. The neuropathic component in persistent postsurgical pain: a systematic literature review / S. Haroutiunian, L. Nikolajsen, N. B. Finnerup, T. S. Jensen // Pain. - 2013. - P. 95-102

16. Mathews K. and others. WSAVA guidelines for recognition, assessment and treatment of pain. - 2014

17. Costigan M. Neuropathic pain: a maladaptive response of the nervous system to damage / M. Costigan, J. Scholz, C. J. Woolf // Annu Rev Neurosci. - 2009. - P. 1-32

18. Katz Joel. Transition from acute to chronic postsurgical pain: risk factors and protective factors / Joel Katz, Ze’evSeltzer // Published online. - 09 Jan. 2014. - P. 723-744

19. Beloeil H. Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (part 1): Hyperalgesia, edema, and systemic cytokines / H. Beloeil, Z. Ababneh, R. Chung [et al.] // Anesthesiology. - 2006. - P. 128-138

20. Morten Rune Blichfeldt-Eckhardt. From acute to chronic postsurgical pain: The Significance of the Acute Pain Response // Dan. Med. J. - 2018. - # 65 (3). - P. 5-326

21. Goldberg S. F. Practical Management of a Regional Anesthesia-Driven Acute Pain Service / S. F. Goldberg, J. P. J. Pozek, E. S. Schwenk, J. L. Baratta [et al.] // Department of Anesthesiology, Thomas Jefferson University, Suite 8290, Gibbon Building, 111 South 11th Street, Philadelphia, PA 19107, USA

22. Rivata C. Mechanisms of regional anaesthesia protection against hyperalgesia and pain chronicization / C. Rivata, L. Bollagb, P. Richebe // Current Opinion in Anaesthesiology. - # 26 (5). - P. 621-625

23. Althaus A. Distinguishing between pain intensity and pain resolution: using acute post-surgical pain trajectories to predict chronic post-surgical pain / A. Althaus, O. Arranz Becker, E. Neugebauer // Eur. J. Pain. - 2014. - # 18. - P. 513-521


Review

For citations:


Voronova M.O., Vatnikov Y.A. ROLE OF REGIONAL ANESTHESIA IN PREVENTING OF ACUTE POSTOPERATIVE PAIN SYNDROME IN DOGS. Russian Journal of Veterinary Pathology. 2021;(4):28-36. (In Russ.) https://doi.org/10.25690/VETPAT.2021.11.79.007

Views: 69


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2949-4826 (Online)