КЛИНИЧЕСКИЕ И ПАТОЛОГОАНАТОМИЧЕСКИЕ ОСОБЕННОСТИ ЭКСПЕРИМЕНТАЛЬНОЙ АКТИНОБАЦИЛЛЕЗНОЙ ПЛЕВРОПНЕВМОНИИ СВИНЕЙ
Abstract
Data on studying clinical and pathologianatomic peculiarities of experimental Actinobacillus pleuropneumoniae
in pigs are shown in the paper. Animals were inoculated intravenously, intratracheally and intranasally.
A typical disease pattern was successfully reproduced using all infection routes. The incubation period
was 6-24 hours. Our observations of experimentally infected pigs showed that the disease had three clinical
forms: superacute, acute and chronic. Hemorrhagic pneumonia, fibrinous pleurisy and pericarditis, as well
as accumulation of bloody fluid in the respiratory cavity were observed at necropsy. In case of a chronic disease
most carcasses showed encapsulated necrosis foci in the lungs. Actinobacillus pleuropneumoniae culture,
used for inoculation, was isolated from viscera samples of dead and emergency slaughtered animals.
in pigs are shown in the paper. Animals were inoculated intravenously, intratracheally and intranasally.
A typical disease pattern was successfully reproduced using all infection routes. The incubation period
was 6-24 hours. Our observations of experimentally infected pigs showed that the disease had three clinical
forms: superacute, acute and chronic. Hemorrhagic pneumonia, fibrinous pleurisy and pericarditis, as well
as accumulation of bloody fluid in the respiratory cavity were observed at necropsy. In case of a chronic disease
most carcasses showed encapsulated necrosis foci in the lungs. Actinobacillus pleuropneumoniae culture,
used for inoculation, was isolated from viscera samples of dead and emergency slaughtered animals.
About the Authors
Д. БирюченковRussian Federation
В. Русалеев
Russian Federation
А. Фроловцева
Russian Federation
References
1. Сидоров, М.А. Гемофилезы животных / М.А. Сидоров, Д.И. Скородумов. М.: Агропромиздат, 1986. С. 29-31.
2. Sebunya, T. N. K. Haemophilus pleuropneumoniae infection in swine: a review / T. N. K. Sebunya, J. R. Saunders // J. Am Vet. Med. Assoc. 1983. Vol. 182. Р. 1331-1337.
3. Dom, P. In vivo association of Actinobacillus pleuropneumoniae serotype 2 with the respiratory epithelium of pigs / P. Dom, F. Haesebrouck, R. Ducatelle, G. Charlier // Infect. Immun. 1994. Vol. 62. P. 1262-1267.
4. Maccines, J. I. Actinobacillus and Haemophilus. Pathogenesis of Bacterial Infections in Animals ed.:C. L. Gyles, C. O. Thoen, / J. I. Maccines, N. L. Smart. Ames: Iowa State University Press. 1993. Vol. 1. P. 188-200.
5. Sidibй, M. Detection of Actinobacillus pleuropneumoniae in the porcine upper respiratory tract as a complement to serological tests / M. Sidibй, S. Messier,S. Lariviйre et al. //Can. J. Vet. Res. 1993. Vol. 57. P. 204-208.
6. Lechtenberg, K. F. Characterization of an Actinobacillus pleuropneumoniae seeder pig challenge-exposure model / K. F. Lechtenberg, T. R. Scryock, G. Moore // Am. J. Res. 1994. Vol. 55, №. 12. P. 201-209.
7. Janetshke, P. Beitrag zur experimentellen Haemophyilusinfektion (Haemophyilus paragemolyticus, Haemophyilus parasuis) bei SPF-Ferkeln / P. Janetshke,P. Kielstein, W. Schonherr et al. // Arch. Exp. Vet. Med. 1977. Vol. 3. P. 347-357.
8. Rosendal, S. Comparative virulence of porcine Haemophyilus bacteria / S. Rosendal, D.A. Boyd, K.A. Gilbride // Can. J. Comp. Med. 1985. Vol. 49. P. 68-74.
9. Болезни свиней / В.А. Сидоркин, В.Г. Гавриш, А.В. Егунова, С.П. Убираев. М.: Аквариум-принт, 2007. С. 385-388.
10. Udeze, F.A. Role of Haemophilus pleuropneumoniae lipopolisacharide endotoxin in the pathogenesis of porcine Haemophilus pleuropneumonia / F.A. Udeze, K.S. Latimer, S. Kadis // J. Am Vet. Med. Assoc. 1987. Vol. 48, №. 5. P. 768-773.
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