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Russian Journal of Veterinary Pathology

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МИКРОКАПСУЛИРОВАНИЕ ДНК И ПЕРСПЕКТИВЫ ИСПОЛЬЗОВАНИЯ В ВИРУСОЛОГИИ

Abstract

The area of nanotechnologies and somatic gene therapy technologies is considered. The paper demonstrates
results of generation of microcapsules having regulated properties (diameter, capsule thickness, membrane
composition and permeability) and the results of Aujeszkys disease viral DNA immobilization in these microcapsules.
The DNA microcapsulation can be used for DNA-vaccine delivery.

About the Authors

С. Белов

Russian Federation


О. Селина

Russian Federation


А. Каталымов

Russian Federation


О. Зиновьева

Russian Federation


References

1. Микрокапсулирование ДНК как способ доставки ДНК вакцин /В.И. Балышева, Н.Н.Власова, О.Е. Селина, [и др.] // Росс. вет. журн. Мелкие домаш- ние и дикие животные. 2007. №1. С. 25-26.

2. ние и дикие животные. 2007. №1. С. 25-26. 2. Combined DNA vaccine encapsulated in microspheres enhanced protection efficacy against Mycobacterium tuberculosis infection of mice /H. Cai, X.D. Hu, D.H. Hu, [et al.] //Vaccine.2005. Vol. 23. Р. 4167-4174.

3. Clark, J.R. Bacterialvirusis as human vaccinsFuture drugs /J.R. Clark, J.В. March //Еxpert Rev. Vaccines. 2004. Vol. 3,4. Р. 463-476

4. Johnson M. E., Mossman S., Cecil T., Evans L. Patent No.:US 2002/0032165 A1 Mar.14, 2002.


Review

For citations:


 ,  ,  ,   . Russian Journal of Veterinary Pathology. 2007;(4):81-84. (In Russ.)

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ISSN 2949-4826 (Online)