ИЗУЧЕНИЕ ДИНАМИКИ ИММУННОГО ОТВЕТА ПОСЛЕ ПРИМЕНЕНИЯ ЭКСПЕРИМЕНТАЛЬНОЙ ВАКЦИНЫ ПРОТИВ ГРИППА И НЬЮКАСЛСКОЙ БОЛЕЗНИ ПТИЦ
Abstract
In this paper the results of investigations aimed at studying the immune response dynamics in poultry after
administration of the experimental vaccine against avian influenza and Newcastle disease are shown. Two
monovalent vaccines against avian influenza and Newcastle disease and three samples of associated vaccines
against avian influenza and Newcastle disease with the antigenic ratio of 60/40; 50/50 and 70/30, respectively,
were used in the trial. The results of the trial suggest that the vaccine sample with the antigenic ratio
of 50/50 possesses the greatest antigenic activity and can be used for further investigations.
administration of the experimental vaccine against avian influenza and Newcastle disease are shown. Two
monovalent vaccines against avian influenza and Newcastle disease and three samples of associated vaccines
against avian influenza and Newcastle disease with the antigenic ratio of 60/40; 50/50 and 70/30, respectively,
were used in the trial. The results of the trial suggest that the vaccine sample with the antigenic ratio
of 50/50 possesses the greatest antigenic activity and can be used for further investigations.
About the Authors
А. ИголкинRussian Federation
М. Циванюк
Russian Federation
Т. Манин
Russian Federation
С. Фролов
Russian Federation
С. Старов
Russian Federation
References
1. Грипп: обзор литературы / Н.С. Дудникова, В.В. Дрыгин, Л.О. Щербакова, А.В. Андриясов. Вла- димир, 2005. 59 с.
2. Эпизоотология и инфекционные болезни сель- скохозяйственных животных / А.А. Конопаткин, И.А. Бакулов, Я.В. Нуйкин [и др.]. М.: Колос, 1984. С. 457-466
3. Swayne, D.E. Influenza / D.E. Swayne, D.A. Halvorson // Diseases of Poultry. 11th ed. Ames, Iowa, 2003. P. 135-160.
4. Highly pathogenic avian influenza // O.I.E. Manual of Standards for Diagnostic Tests and Vaccines. - Paris, 2004. Vol. 1. P. 258-269.
5. Mayo, M. A. Virus taxonomy-Houston 2002 / M. A. Mayo // Arch. Virol. 2002. Vol. 147. P. 1071-1076.
Review
For citations:
, , , , . Russian Journal of Veterinary Pathology. 2007;(4):152-154. (In Russ.)
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