ИММУНОБИОЛОГИЧЕСКИЕ СВОЙСТВА ВАКЦИНЫ ПРОТИВ ПАСТЕРЕЛЛЕЗА КРОЛИКОВ
Abstract
The paper presents results of studying immunobiological properties of mono- and bivalent vaccines against
rabbit pasteurellosis produced from formalin-inactivated bacteria Pasturella multocida (serovars A:1 and
A:3). Blood sera obtained from animals, immunized by monovalent vaccines, were positive in the precipitation
test only with homologous antigens. Animals, immunized by monovalent vaccines against pasteurellosis,
were protected only if a homologous strain was used for inoculation. Two different serovariants of P.
multocida commonly isolated from rabbits increase the preventive efficiency of the bivalent vaccine if they
are used in its composition.
rabbit pasteurellosis produced from formalin-inactivated bacteria Pasturella multocida (serovars A:1 and
A:3). Blood sera obtained from animals, immunized by monovalent vaccines, were positive in the precipitation
test only with homologous antigens. Animals, immunized by monovalent vaccines against pasteurellosis,
were protected only if a homologous strain was used for inoculation. Two different serovariants of P.
multocida commonly isolated from rabbits increase the preventive efficiency of the bivalent vaccine if they
are used in its composition.
About the Authors
А. ПотехинRussian Federation
Ф. Ширяев
Russian Federation
О. Бородина
Russian Federation
References
1. Заерко, В.И. Разработка и внедрение универсаль- ной технологии изготовления, контроля и при- менения вакцин против пастереллеза животных: дис. в форме науч. докл д-ра вет.наук / Заерко В.И. М., 2000. С. 35.
2. Ручнова, О.И. Определение антигенного родства изолятов Pasteurella multocida, выделенных на территории Российской Федерации / О.И. Ручно- ва, О.В. Прунтова // Вет. патология. 2006. №4 (19). С. 113-115.
3. Brogden, K.A. Comparison of Pasteurella multocida serotyping sistems / K. A. Brogden, R. A. Packer // Am. J. Vet. Res. 1979. Vol. 40, №9. P. 1332-1335.
4. Carter, G.R. The preparation and use of vaccines for the prevention of pasteurellosis / G. R. Carter // Can. Vet. J. 1961. N 2. P. 96.
5. Heddleston, K.L. Fowl cholera: gel diffusion precipitin test for serotyping Pasteurella multocida from a viam species / K. L. Heddleston, J. E. Galanter, P. A. Rebers // Avian Dis. 1972. Vol.16. P.925-935.
6. Killian, N. Haemophilus, Pasteurella and Actinobacillus / N. Killian. London: Acad. Press, 1981. P. 293.
7. Percy, D.H. Experimental pneumonia in rabbits inoculated with strains of P. multocida / D. H. Percy, J. L. Bhasin, S. Rosendal // Can. J. Vet. Res. 1986. Vol. 50, №1. P. 36-41.
8. Rimler, R.B. Lipopolisacharides of the Heddleston serotypes of Pasteurella multocida / R. B. Rimler, P. A. Rebers, M. Phillips // Am. J. Vet. Res. 1984. Vol. 45. P. 759-763.
9. Rimler, R.B. Pasteurella multocida isolated from rabbit and swine: serologic types and toxin production / R. B. Rimler, K. A. Brogden // Am. J. Vet. Res. 1986. Vol. 47. P. 730-737.
10. Rimler, R.B. Pasteurella and pasteurellosis / R. B. Rimler, K. R. Rhoades. London: Acad. Press, 1989. P. 37-73.
11. Sokkar, S.M. Pathogenesis of P. multocida in experimentally infected rabbits / S. M. Sokkar, M. A. Mohamed, H. Fetaih // Arch. Еxp. Vet. Med. 1987. Bd. 41, № 4. S. 516-521.
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, , . Russian Journal of Veterinary Pathology. 2007;(4):179-182. (In Russ.)
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