БИОЛОГИЧЕСКИЕ СВОЙСТВА ИЗОЛЯТА ВИРУСА ГРИППА ПТИЦ A/DUCK/ NOVOSIBIRSK/2/2005 H5N1
Abstract
Field isolate of avian influenza (AI) virus has been recovered from the pathological material from a domestic
duck, obtained from the outbreak in the Novosibirsk Oblast in 2005. After the 1st passage on SPF chicken
embryos, extraembryo fluid activity in hemagglutination test was 1:256, and in hemagglutination inhibition
test this fluid reacted only with the specific serum against AI virus subtype H5. Embryos died after 48 hours
post inoculation. Intravenous pathogenicity index was 2.87, it proved that the virus was highly pathogenic.
Thus, as a result of the examinations, biological properties of the recovered AI virus isolate were determined,
and this isolate was identified as an etiological agent of the disease outbreak in this region.
duck, obtained from the outbreak in the Novosibirsk Oblast in 2005. After the 1st passage on SPF chicken
embryos, extraembryo fluid activity in hemagglutination test was 1:256, and in hemagglutination inhibition
test this fluid reacted only with the specific serum against AI virus subtype H5. Embryos died after 48 hours
post inoculation. Intravenous pathogenicity index was 2.87, it proved that the virus was highly pathogenic.
Thus, as a result of the examinations, biological properties of the recovered AI virus isolate were determined,
and this isolate was identified as an etiological agent of the disease outbreak in this region.
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Review
For citations:
, . Russian Journal of Veterinary Pathology. 2006;(4):60-63. (In Russ.)
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