MICROSTRUCTURE OF BLOOD-BRAIN BARRIER IN BIRDS OF DIFFERENT AGES
Abstract
The aim of this work was to study of the ultramicroscopic structure of the blood-brain barrier from broiler chickens of different ages. To study the brain was taken brain of broiler chickens 1, 20 and 38 days old. After studies can draw the following conclusion: after hatching chicken the blood-brain barrier has fully formed structure. Such barrier components as the basement membrane, endothelial cells, glial «clutch» are present. Endothelial cells have a close contact with each other. The layer of the basement membrane is structured. Glial cells surround the vessels tightly. Further barrier structure is maintained. The elements are becoming more structured. Pericytes are viewed. Nevertheless, marked perivascular edema and enlightenment in the cytoplasm of astrocyte ends. In the finishing period of the productivity of broiler chickens the blood-brain barrier has not lost its morphological identity. Endothelial cells become are larger, sometimes swollen. Regarding glial cell, they show signs of degradation in the form of cleaning of nucleoplasm and destruction of the internal structure. Furthermore, there is perivascular edema, which indicates the pathological processes in the structure of the blood-brain barrier.
About the Authors
Lyudmila Ivanovna Drozdova
Уральский ГАУ
Russian Federation
Russian Federation
Svetlana Victorovna Madonova
Уральский ГАУ
Russian Federation
Russian Federation
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Review
For citations:
Drozdova L.I., Madonova S.V. MICROSTRUCTURE OF BLOOD-BRAIN BARRIER IN BIRDS OF DIFFERENT AGES. Russian Journal of Veterinary Pathology. 2015;(3):59-64. (In Russ.)
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