MINERAL ELEMENTS IN THE METABOLISM OF PATHOGENIC BACTERIA

Abstract

This paper presents a review of the literature on the role of mineral elements in the life and metabolism of pathogenic bacteria. There are the data on the functional significance of essential elements in the metabolic processes of microorganisms, the methods of their transport into the cell, the role of the mineral elements in the relationship with the microorganism - host in vivo. There are also data on the value mineral elements for a number of pathogenic microorganisms and the displaying a functional part of the iron ions in the breathing process, growth and virulence of toxin. In the article are shown the results of work on the optimization of culture media for the industrial production of bacterial antigens in the manufacture of preventive and curative drugs for the composition of the mineral elements, the positive effect of complex organic compounds of macro- and micronutrients, particularly iron on growth of microorganisms, promising biotechnology serial production of bacterial antigens and vaccines have proved to be an additive of complex iron compounds with the peptides. On the model of bacterial swine erysipelas reliably demonstrated the stimulating effect of the iron-containing preparation «Peptofer» on the accumulation of bacterial mass by increasing the viability, safety of initial growth properties, morphological and biochemical indices