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DEVELOPMENT OF A METHOD FOR ASSESSING THE IMMUNOLOGICAL REACTIVITY OF ANIMALS

https://doi.org/10.25690/VETPAT.2021.41.89.001

Abstract

The study of immunological relationships in the functional system «mother-placenta-ospring» can make a significant contribution to the solution of the issue of increasing the safety of the livestock of newborn animals. The reason for significant mortality rate may be the pathology of pregnancy, which is characterized by toxicosis, fetal mortality and the birth of an unviable ofispring. The pathology of antenatal development in animals has not been adequately studied. Antenatal pathology of animals often manifests itself in the form of congenital malformations (anomalies) of development. Congenital malformations are usually called defects that have arisen during intrauterine development. However, congenital defects are also observed during postnatal development, as a consequence of the violation of the further formation of organs in animals. There is a need to develop a method for determining the immunological reactivity of an animal organism, which would allow assessing the combined functional state of the cell-mediated immunological reactivity of innate and acquired immunity in the mother-placenta-ofispring functional system and to determine the factors causing immunosuppression. Determination of the immunological reactivity of the organism of animals included the study of blood by conducting a biological test, which is used as the biological activity of erythrocytes in the HCT test and in terms of their sorption activity - more than 40 % of the animals are classified as individuals with reduced immunological reactivity among a homogeneous sample.

About the Authors

A. V. Agarkov
«Stavropol State Agrarian University»
Russian Federation


A. F. Dmitriev
«Stavropol State Agrarian University»
Russian Federation


A. N. Kvochko
«Stavropol State Agrarian University»
Russian Federation


N. V. Agarkov
«Stavropol State Agrarian University»
Russian Federation


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Review

For citations:


Agarkov A.V., Dmitriev A.F., Kvochko A.N., Agarkov N.V. DEVELOPMENT OF A METHOD FOR ASSESSING THE IMMUNOLOGICAL REACTIVITY OF ANIMALS. Russian Journal of Veterinary Pathology. 2021;(1):43-47. (In Russ.) https://doi.org/10.25690/VETPAT.2021.41.89.001

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