ИММУНОСТИМУЛИРУЮЩИЕ СВОЙСТВА СА-МОДИФИЦИРОВАННОЙ РНК ПРИ РЯДЕ ВИРУСНЫХ БОЛЕЗНЕЙ СЕЛЬСКОХОЗЯЙСТВЕННЫХ ЖИВОТНЫХ

Abstract

The experimental data regarding immunopotentiating activities of the Ca - modifying RNA against FMD and Newcastle disease of poultry are presented. The optimal dose of protection and optimal time of injection of the Ca - modifying RNA on guinea pigs after infection of foot-and-mouth are determined. In the presented work also shown that using of preparation simultaneously with the vaccination agains Newcastle disease, significantly enhancing the effect of the vaccine. The possible mechanisms of the preparation for the potentiating of the primary and secondary immune response which are possible connected with the ability of the preparation to stimulate the synthesis of endogenous interferon with the furter antiviral activity, as well as the strengthening of the immune response of T-and B-cells are presented in the work.