КОМПЛЕКСНОЕ ИСПОЛЬЗОВАНИЕ СЕРОЛОГИЧЕСКИХ МЕТОДОВ ДЛЯ ОБНАРУЖЕНИЯ АНТИТЕЛ К ВИРУСУ ГРИППА ПТИЦ ПОДТИПА Н5 В СЫВОРОТКАХ КРОВИ ДИКИХ И ДОМАШНИХ ПТИЦ
Abstract
Specific antibodies to highly virulent avian influenza virus type A subtype H5 were detected in blood sera
from wild waterfowl by serological tests during a complex study, while in blood sera from chickens non-vaccinated
against avian influenza antibodies to that subtype were not detected. After immunization of poultry
with inactivated H5N1 avian influenza vaccine specific antibodies were detected on day 28-35 using hemagglutination
inhibition test at titres not less than 7 log2.
from wild waterfowl by serological tests during a complex study, while in blood sera from chickens non-vaccinated
against avian influenza antibodies to that subtype were not detected. After immunization of poultry
with inactivated H5N1 avian influenza vaccine specific antibodies were detected on day 28-35 using hemagglutination
inhibition test at titres not less than 7 log2.
About the Authors
Н. ЛуговскаяRussian Federation
М. Циванюк
Russian Federation
С. Фролов
Russian Federation
Н. Мудрак
Russian Federation
В. Дрыгин
Russian Federation
А. Борисов
Russian Federation
References
1. Лагуткин Н., Лутовинов В. Непредсказуемость гриппа // Птицеводство. 2001. № 6. C. 27-30.
2. Munster V., Wallensten A., Bestebroer T.M. et al. Fouchier, R.A.M. Characterization of novel influenza a virus hemagglutinin subtype (H16) obtained from black-headed gulls //Journal of Virology. 2005. Mar. P. 2814-2822.
3. Hinshaw V.S., Shreerar M.G., Larsen D. Specific antibody responses and generation of antigenic variants in chickens immunized against a virulent avian influenza virus // Avian Disease. 1990. V. 34. Р. 80-86.
4. Manual of diagnostic tests and vaccines for terrestrial animals (mammals, birds and bees) // OIE. Fifth Edition. 2004.
5. Swayne D.E., Garcia M., Beck J.R., Kinney N., SuarezD.L. Protection against diverse highly pathogenic avian influenza viruses in chickens immunized with a recombinant fowl pox vaccine containing an H5 avian influenza hemagglutinin gene insert // Vaccine. 2000. V. 18. P. 1088-1095.
Review
For citations:
, , , , , . Russian Journal of Veterinary Pathology. 2006;(4):63-67. (In Russ.)
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