MORPHOFUNCTIONAL CHARACTERISTICS OF BLOOD LEUKOCYTES OF CHICKENS VACCINATED AGAINST GUMBORO AND INFECTIOUS CORYZAE
Abstract
Morphological and functional characteristics of chicken blood leukocytes vaccinated against Gumboro disease and infectious coryzae are studied. Is investigated the total amount of white blood cells and their cellular structure in the post-vaccination period. The functional state of the cells assessed by their phagocytic activity with latex particles and the ability to generate active oxygen forms. The total volume of production of reactive oxygen species, activation index and phagocytic activity of leukocytes is determined. Effect of vaccination on the morphological and functional parameters of blood leukocytes of chickens is established. Immunization induced leukocytosis and lymphocytosis development after vaccination against Gumboro disease and psevdoeozinophilia and monocytosis after vaccination against infectious coryzae. Immunization stimulated phagocytic activity and increased the intensity of free radical processes in the blood cells. Significant amounts of reactive oxygen forms generated by the immunized birds were carrying potential risk the cell membrane damage and showed a decrease in the potential of phagocytes to respond to additional antigenic stimulation.
About the Authors
Pavel Yur'evich Tsarev
ФГБОУ ВО «Красноярский государственный аграрный университет»
Russian Federation
Russian Federation
Natalia Vladimirovna Donkova
ФГБОУ ВО «Красноярский государственный аграрный университет»
Russian Federation
Russian Federation
Eugenia Turitsyna
ФГБОУ ВО «Красноярский государственный аграрный университет»
Russian Federation
Russian Federation
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Review
For citations:
Tsarev P.Yu., Donkova N.V., Turitsyna E. MORPHOFUNCTIONAL CHARACTERISTICS OF BLOOD LEUKOCYTES OF CHICKENS VACCINATED AGAINST GUMBORO AND INFECTIOUS CORYZAE. Russian Journal of Veterinary Pathology. 2016;(4):10-16. (In Russ.)
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