ОПРЕДЕЛЕНИЕ ПРИВИВОЧНОЙ ДОЗЫ АССОЦИИРОВАННОЙ ВАКЦИНЫ ПРОТИВ ПАРВОВИРУСНОЙ, РЕОВИРУСНОЙ, ГЕРПЕСВИРУСНОЙ ТИПА I ИНФЕКЦИЙ И ВИРУСНОЙ ДИАРЕИ - БОЛЕЗНИ СЛИЗИСТЫХ ОБОЛОЧЕК КРУПНОГО РОГАТОГО СКОТА

Abstract

Presents the results of the selection of the optimal dose of combined vaccine against parvovirus, reovirus, herpesvirus type I infections and viral diarrhea - mucosal disease for cattle in different age groups of cattle. To enhance immunogenicity of combined vaccine tested oil adjuvant and aluminium hydroxide adjuvant. The maximum level of gumoral specific antibody in experimental animals registered after the second vaccination. Found that optimal dose of emulsion vaccine: for calves 10-20 days of age - 1 ml, for heavily pregnant cows and heifers and heifers unpregnant period - 2 ml, optimal dose of combined vaccine with aluminium hydroxide: 3 ml and 5 ml respectively. It is shown that the associated oil based adjuvant combined vaccine provides specific antibodies in the higher titles of the components that make up the vaccine than aluminium hydroxide.